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    God/dess threlayer's Avatar
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    Default Sometimes Mamma is Right

    This is an important article about staying healthy, by doing pretty much as Mamma told you....

    Lifestyle Changes Boost Enzyme Regulating Cell Aging

    Adjustments to diet, exercise increased telomerase levels 29%, cut 'bad' cholesterol

    Posted September 16, 2008 (as found in USNews)


    TUESDAY, Sept. 16 (HealthDay News) -- Major lifestyle changes can help improve levels of an enzyme called telomerase that controls cell aging, say California researchers.
    Telomerase repairs and lengthens telomeres, which are DNA-protein complexes at the end of chromosomes that directly affect how quickly cells age. As telomeres become shorter and their structural integrity weakens, cells age and die more quickly, according to background information in a University of California, Irvine, new release. Shortening of telomeres is emerging as a marker of disease risk and premature death in many types of cancer, including prostate, lung, breast and colorectal cancers.
    In this study, Dr. Dean Ornish, a professor of medicine at the Preventive Medicine Research Institute in Sausalito, Calif., and his colleagues at the University of California, San Francisco, asked 30 men diagnosed with low-risk prostate cancer to make significant lifestyle changes.
    The changes included eating a diet with only 10 percent of calories from fat, low in refined sugars, and rich in whole foods, fruit and vegetables. They supplemented their diet with vitamins and fish oil and did moderate aerobic exercise, stress management, relaxation techniques, and breathing exercises.
    The men's telomerase levels were measured at the start of the study and again at three months. At that time, the researchers found a 29 percent increase in telomerase levels and a decrease in "bad" (LDL) cholesterol.
    The findings were published online and will appear in the November print issue of The Lancet Oncology.
    "To our knowledge, we have reported here the first longitudinal study showing that comprehensive lifestyle changes -- or any intervention -- are significantly associated with increases in cellular telomerase activity levels and telomere maintenance capacity in immune system cells," the study authors wrote.
    "The implications of this study are not limited to men with prostate cancer. Comprehensive lifestyle changes may cause improvements in telomerase and telomeres that may be beneficial to the general population as well," Ornish said in the news release.
    I loved going to strip clubs; I actually made some friends there. Now things are different for the clubs and for me. As a result I am not as happy.

    Customers are not entitled to grope, disrespect, or rob strippers. This is their job, not their hobby, and they all need income. Clubs are not just some erotic show for guys to view while drinking.

    NOTE: anything I post here, outside of a direct quote, is my opinion only, which I am entitled to. Take it for what you estimate it is worth.

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    God/dess LuckyOne's Avatar
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    Default Re: Sometimes Mamma is Right

    I have exceptionally high HDL cholesterol and low LDL cholesterol. Its the only thing on 3 pages of bloodwork that tested out of the normal range. I'm super proud of that because I think I've earned it. I eat really healthy and workout almost every day.

    Thanks for the info!

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    God/dess threlayer's Avatar
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    Default Re: Sometimes Mamma is Right

    This enzyme, telomerase, that controls cell aging is the Methuselah factor.
    ...DNA-protein complexes at the end of chromosomes that directly affect how quickly cells age. As telomeres become shorter and their structural integrity weakens, cells age and die more quickly...
    This is important because as aging is in fact too many cells dying and not being replaced by viable substitutes. This produces weaknesses and allows diseases to occur.

    I know the article did not delve into this much, but you could look it up (eg, http://en.wikipedia.org/wiki/Telomerase). Sorry I'm not much of an educator. But I posted this info because this seems to be pretty significant development for all of us.
    I loved going to strip clubs; I actually made some friends there. Now things are different for the clubs and for me. As a result I am not as happy.

    Customers are not entitled to grope, disrespect, or rob strippers. This is their job, not their hobby, and they all need income. Clubs are not just some erotic show for guys to view while drinking.

    NOTE: anything I post here, outside of a direct quote, is my opinion only, which I am entitled to. Take it for what you estimate it is worth.

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    Banned jasmine's Avatar
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    Default Re: Sometimes Mamma is Right

    If only researchers could find a way to introduce telomerase therapies without triggering rapidly growing cancers. Many researchers think this will be the big breakthrough in extending human lifespan.

    The Vit A derivatives show some promise, but right now they are only moderately effective as a topical treatment and come with a myriad of side-effects.

    BTW - I had no idea anyone else was interested in this sort of thing. When I gave my little telomeres speech on the retin-a thread a while back I think the only response I got was a "Whoa!" Makes me feel less geeky!

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    God/dess threlayer's Avatar
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    Default Re: Sometimes Mamma is Right

    Yes. I wasn't aware if the Vit A tie in.

    The Geron Corp has been researching this long time. Back in the late 90s they announced some important findings. That's when I got hooked into this work, especially after I discussed it with some health systems administrators and they stated their great interest.

    You know, I've never been able to read past the first page on a SciAmer biochem article (not boring, just confusing), though it seems any of the other articles are no problem. I might not understand what's going on in depth, but I certainly get the jist of this research.
    I loved going to strip clubs; I actually made some friends there. Now things are different for the clubs and for me. As a result I am not as happy.

    Customers are not entitled to grope, disrespect, or rob strippers. This is their job, not their hobby, and they all need income. Clubs are not just some erotic show for guys to view while drinking.

    NOTE: anything I post here, outside of a direct quote, is my opinion only, which I am entitled to. Take it for what you estimate it is worth.

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