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Thread: Antidepressants (ATTN: Mediocrity)

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    Default Antidepressants (ATTN: Mediocrity)

    I haven't been able to sleep lately..... a few days ago I ended up taking six Unisom trying to sleep, and still couldn't..... I ended up going to see a psychiatrist, because I also have chronic anxiety. She prescribed me Pristiq and Temazepam (I asked for this) to help me.

    I took Pristiq last night for the second day, and stayed up ALL. NIGHT. I felt like I was on ecstasy minus the euphoria, like the cool tingly, chills down your spine, like I had vicks vapo rub inside my brain, right around the nape of my neck. Anyone who has done X will know what I'm talking about. My face was greasy and pupils dilated. The feeling was hitting me in waves waking me up, so I never made it into a deep sleep. This morning I woke up, drank my coffee, and as I was about to get into the shower it hit me.....

    I had a full blown panic attack, maybe the worst I've ever had. It felt like I was leaving my body, floating. It was an uncontrollable overwhelming feeling like I took too much of something and my body couldn't handle it, so I was going into cardiac arrest. It felt like this one time I took a lot of ecstasy and it all hit me at once, overwhelming me, and I felt like I was overdosing. This was years ago, but the same feeling, I really thought I was dying. I ran into my roommate's room and told her to call 911, I was shaking uncontrollably and trying to make myself puke, desperate to get whatever drug out of my body.

    I finally calmed down, but it's been 24 hours since I took that Pristiq, and I still feel like I'm rolling, minus all the happy feelings. I never want to take this shit again! I've heard it has the worst withdrawals out of any pill. I just need something that's not a benzopiadine that I can take for my anxiety and to help fall asleep. I really dislike Ambien, Sonata, and all those as well. I don' t know if my reaction is normal (it didn't feel like it) or if this medication is not for me.

    Anybody have any experience or advice for me?
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    Default Re: Antidepressants (ATTN: Mediocrity)

    That almost sounds like an allergic reaction. Might not be the medication for you at all. Call your doc and tell them in detail what happened and see if they can switch you to something else.

    I would be afraid to take it again.

    Unisom works for me sometimes but it tends to lose effectiveness over time so I try to take a week or two off. There are 2 kinds tho - the doxylamine kind of unisom is the only one that works for me.

    Maybe also try some herbals? chamomile tea helps me sometimes if I make it really really strong with some honey or sugar to sweeten it a bit. It's good for both sleep and calming nerves.


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    Default Re: Antidepressants (ATTN: Mediocrity)

    I take Pristiq, and it gives me terrible insomnia for the first week or so I start taking it. I had a few other side effects, such as the ecstacy-like feelings and dialated pupils. I also had very bad dry mouth, and some others. They all pretty much went away on their own after a little bit. That is common on anti-depressants, but if you are having such a strong reaction then they are probably not for you.

    Everyone is different, and personally I like Pristiq, but I've had bad reactions to other drugs. For example, Zoloft made me so sick to my stomach I could barely function.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    try taking some valerian root capsules. if i take them an hour later i will be sound asleep. also it doesn't leave you drowsy or anything in the morning. and if you take a low dose they will just make you feel really calm and peaceful instead of making you wanna fall asleep.
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    Default Re: Antidepressants (ATTN: Mediocrity)

    I'm so sorry that you went through that. Unfortunately, it seems like when you're trying to be proactive about your mental health you'll likely find a few meds that are basically kryptonite to you... most everyone I know who's been on meds (myself included) has had at least one traumatic experience. I'm curious if those side effects would eventually dissipate... The question is, is it worth the wait (ie will it actually work as intended) and can you realistically function in your daily activities while being stuck in that horrific of a transitional stage in the mean time? I would try get an appointment asap to talk to your doctor about what happened. Maybe ask about Vistaril (Hydroxyzine), too. I was on that for a few years for anxiety and insomnia... I didn't have much in the way of side effects, aside from drowniness if I stayed awake on it and sometimes grogginess after sleeping on it; nothing a cup or two of coffee couldn't take care of, though. It's an antihisthamine, as well as an antianxiety, a sleep aid, and an antinausea. It's kind of like Benadryl's older, stronger brother, so if you can take Benadryl w/o any weird side effects, it might be worth a shot. I hope everything works out for you.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    If you don't want to take benzos try paxil. I don't take it daily( I know it's know it's not how it's suppose to be used) but I take a half every other day when my panic, anxiety gets out of control. I've had insomnia for around 4 years and I do take kolonopin but paxil will help with that and anxiety.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Oh and I was prescribed tamazapam too it's a benzo too I believe prescribed for sleep and I didn;t really like it.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    I've taken several medications for sleep and anxiety over the years. I'll give you a list and some thoughts about all of them aside from Ambien and benzos.

    Clonidine: This is a blood pressure medication but it worked very well for my insomnia before I gained a tolerance. It doesn't do much for anxiety, though, and you definitely should not take more than prescribed. The only side effect for me was dizziness, but this wasn't a problem as long as I got in bed as soon as it started to kick in. Last I knew using it for insomnia was seriously off label so doctors might not think to prescribe it or feel comfortable with it, but I loved it while it worked.

    Trazadone: Worst migraine ever, but I've heard good things from other people.

    Hydroxyzine: I used this throughout the day for anxiety with moderate success and also as a supplement to Clonidine when my tolerance started to increase. I'm not sure how long it would be effective for insomnia if you also took it for anxiety throughout the day. I don't remember any side effects though.

    Remeron: I slept for 10 hours a night and I had no anxiety, but that was because I didn't have many feelings at all. All I did was sleep and eat. Stopped taking it after a couple of weeks.

    Seroquel: This is what I currently take, but only because I've become tolerant to so many other medications. There are many problems with this drug, especially in high dosages (tardive dyskinesia, weight gain and associated problems, apathy) but in a worst case scenario a small dose could greatly improve the quality of your life. I had an incompetent doctor who prescribed too high of a dose and I experienced all the side effects of Remeron x10. On Remeron I was still able to care enough about my weight/health to stop taking it when I noticed a problem. With Seroquel I did not give a fuck about anything so for a year I stayed in bed most of the day watching Disney movies and eating horrible food. I would also binge in my sleep. I gained 30lbs within three months, but luckily (kind of?) it leveled off there. Now I'm on 25-50mg a night down from 300. I lost the 30lbs while on this dose so weight gain isn't inevitable, but I have modified my eating schedule to allow for a late night binge which may be unacceptable for your diet. Either way, this stuff works and has been a lifesaver, but I certainly wouldn't recommend this unless all else fails.

    Hope this helps!

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    Default Re: Antidepressants (ATTN: Mediocrity)

    I was on several anti-depressants that gave me this effect. Its actually serotonin poisoning. You don't have a seratonin imbalance. Are you depressed? Why do you need Pristiq?

    Pristiq is the newest drugs by the makers of Effexor because Effexor went generic an they need something else to make money off of. I'm not anti-pharma by any means. But unless you are really seratonin deprived and majorly depressed, stay away from this.

    I take 25 mg of Seroquel and night to sleep and for anxiety and it is lovely, works perfectly, doesn't fuck me up like any Seratonin reuptake based med. But it can cause weight gain because I swear, shit gives you the MUNCHIES right before it sedates you enough to make it easy to sleep. LOL. Its kind of like weed without the feeling of being mentally stoned, just physically sedate and hungry.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Temazapan is barely even a benzo, that shit is weak. I have insomnia issues, here is what I have to do, give it a shot:

    1. take 25 mg of Seroquel and eat something. If you don't eat something, you'll get Seroq-munchies.
    2.Takes about 45 min-an hour to metabolize, so take it easy. Do NOT try to drive. Seroquel physically sedates your body, arms and legs will feel very "loose" and almost weakened.

    3. As soon as you feel "loosey-goosey" physically, its time to relax and let your brain shut down. Unlike benzos or hypnotics like ambien, Seroquel won't cause you amnesia or even quasi-euphoria. ITs mostly a physical sedative, but there is a relaxing mental component to it. But it won't shut your brain off completely. This is actually a good thing, you still have your wits about you and can train yourself.

    4. Dark room. Eye mask and ear plugs. Legs elevated. Getting rid of outside stimulus helps quiet the brain. Elevating legs I can't explain, guess it brings more blood to the body but its very helpful.

    Give it a whirl, good luck!

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Your comments about low doses of Seroquel are dead on, KS.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Lorazepam help but it gets additive in the end, but it kicks in faster

    Clonazepam helps, but its slower release and isnt as craving.

    Both were given to me by my therapist.. I like to take the second one, it kicks in after 30 mins to an hr and should last 4-6 hrs.
    Before that I couldn't sleep longer than 5 hours! I "forgot' to take one yesterday, and had a tiring day where my body was fallng asleep but my mind wasnt, I barely got 6 hours! My therapists gave them to them only for sleeping purposes, both are cheap!

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    Default Re: Antidepressants (ATTN: Mediocrity)

    The only reason I love temezepam is because I HATE xanax, and it is so much more mild. I don't feel fucked up the next day.

    I never thought about Seroquel, I will ask about this though on Thursday when Is see my shrink again. Pristiq is NOT for me.... I have chronic anxiety.... but this was not the medication to fix it, for sure.... I just cannot give it a week to kick in, that panic attack was way too intense, along with the prolonged ecstasy feelings....
    Quote Originally Posted by AznExtasy View Post
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    Default Re: Antidepressants (ATTN: Mediocrity)

    Quote Originally Posted by KS_Stevia View Post
    I was on several anti-depressants that gave me this effect. Its actually serotonin poisoning. You don't have a seratonin imbalance. Are you depressed? Why do you need Pristiq?

    Pristiq is the newest drugs by the makers of Effexor because Effexor went generic an they need something else to make money off of. I'm not anti-pharma by any means. But unless you are really seratonin deprived and majorly depressed, stay away from this.

    I take 25 mg of Seroquel and night to sleep and for anxiety and it is lovely, works perfectly, doesn't fuck me up like any Seratonin reuptake based med. But it can cause weight gain because I swear, shit gives you the MUNCHIES right before it sedates you enough to make it easy to sleep. LOL. Its kind of like weed without the feeling of being mentally stoned, just physically sedate and hungry.


    Which ones were you on?
    Quote Originally Posted by AznExtasy View Post
    LMAO!!!!!!!!!!!!!!!!!!!!!!
    You can say that again.. not just on here but men in general. Guys are so damn lame, the only way they can halfway make up for it is by opening their wallets.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    JD, please be careful and listen to your body!

    Your experience sounds similar to one I had a year and a half ago that I am still recovering from. I had never taken an antidepressant before and got prescribed Wellbutrin. HUGE mistake -- I also have anxiety issues and clearly anything in the norepinephrine reuptake inhibitor class of drugs is not for me.

    The first time I took it I felt a high, but a weird, pupils dilated cracked out high. But I liked that my appetite disappeared and my sex drive went through the roof, so I kept taking it.

    Fast forward two weeks -- still cracked out, except I am chronically dehydrated, picking at my skin, severely constipated, my blood pressure has dropped to 70/50, and I feel only halfway in the world (like I am going to float away...just like you described). On day 12 of taking it I called my doctor because I couldn't go #2 and he said to increase the dose and wait to adjust. The next day I had a seizure.

    I immediately went off it but it blew out my stress response/endocrine system so badly that it has taken a year and a half of research and a strict health regimen to get back to normal. Normal meaning that I am not having panic attacks, my blood pressure is minimum 90/60, heart palpatations managable, weight/blood sugar/electrolytes stablized, and that I am able to shit on my own. It has been a nightmare. I thought I would never be the same and in some ways I am not...but I'm still healing.

    Just be careful, pharmaceuticals are hardcore and I would never want anyone to go through that. I'm only 23 and there were many times in the past year that I honestly thought my body was falling apart and I was going to die.


    ------
    One last note, beware of Ativan. My mom took it for anxiety and it's been a nightmare for her to get off it.
    Last edited by glitzy; 08-28-2011 at 10:08 AM. Reason: [*edit: spelling mistake]

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Have you tried Trazadone? I would talk to your pharmacist and see what they say about your reaction and see what they recommend. They often know more about specific drugs than your doc.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    I texted you about the supplemental way to go for depression, but I have a few other things to add.

    A) Have you tried valerian tincture for sleep? It sounds totally lame but it really, really helps.
    B) I've had full blown "I'm dying" panic attacks from mixing new drugs and caffiene. Switch to decaf until you get this all sorted out. Caffeine isn't going to do you any favours.
    C) KS's comments about serotonin poisoning are an interesting theory and may be on point. Bring this up with your doctor ASAP because serotonin syndrome can be pretty serious if not acknowledged and treated.
    D) Acknowledging what's REALLY bothering you is going to help too. I have a lot of trouble asking for help and I repress everything. I went to the ER when we were in Vancouver because I had a panic attack in my sleep that woke me up. I had them do an EKG, ultrasound my heart and everything, convinced I was about to have cardiac collapse. After a lot of talking and addressing what was bugging me, the attacks stopped. I know you're in a very transitional period, that's a hard spot to be in. But you NEED a support system.

    I'll be back as I think of more. Call me if you need me.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Quote Originally Posted by mediocrity View Post
    D) Acknowledging what's REALLY bothering you is going to help too. I have a lot of trouble asking for help and I repress everything. I went to the ER when we were in Vancouver because I had a panic attack in my sleep that woke me up. I had them do an EKG, ultrasound my heart and everything, convinced I was about to have cardiac collapse. After a lot of talking and addressing what was bugging me, the attacks stopped. I know you're in a very transitional period, that's a hard spot to be in. But you NEED a support system.
    Weird, I woke up with a panic attack while traveling in Vancouver and went to St Pauls with the exact same request! I thought I was going to die. It was during a very isolated and unstable time in my life when my health problems were really bad but my greater life problems were the real issue.

    I ended up going to a naturopath and in a funny twist of events she became a close friend while I was here. Once I had someone besides my boyfriend to hash things out with I improved a lot.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    One last thing: how honest were you with your dr about any and all supplements, OTC drugs and anything else? Because any and all anti-coagulants -even naproxen and aspirin according to the pamphlets- will have a drug reaction. The literature says even TRYPTOPHAN can interact with it.

    I say completely ditch the Pristiq. Try the supplements for two weeks, and if you see no improvement, go to another Dr for a second opinion.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    I was completely honest with her about everything. She wanted to first put me on Vyvanse and then possibly Lexapro. I insisted on Pristiq over Lexapro because I've heard Lexapro can make you gain weight but Pristiq won't. I only had 45 minutes with her, and I was pretty much hysterical crying the whole time, so my main concern was getting something so I could sleep/be calm enough to function. She had to ask a series of questions in order to prescribe me a benzopiadine, so we didn't have time to discuss much else. I am supposed to go back on Thursday though....

    I'm usually fine as long as I take a diet pill and start drinking cups of coffee every morning, it's enough to distract me and keep me focused and productive, but if I don't do that, it's hard even to wake up. It's like I don't want to face my life sometimes. I work so hard to change my life, and I have, but in the most important ways it's stagnant, repetitive, like I repeat the same cycle over and over with the same negative result. It's too much to handle, especially this last time. That's why I thought an anti depressant would work well for me.

    Thank you everybody for your support!
    Quote Originally Posted by AznExtasy View Post
    LMAO!!!!!!!!!!!!!!!!!!!!!!
    You can say that again.. not just on here but men in general. Guys are so damn lame, the only way they can halfway make up for it is by opening their wallets.

    Created by MyFitnessPal.com - Tools

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    Default Re: Antidepressants (ATTN: Mediocrity)

    ^ I bet it was the diet pill that interacted badly with the prstiq. I was going to say that the other day but forgot if you take them. You're not supposed to take energy or diet pills with ssri's as they can cause serrotonin syndrome. I've had bad reactions before when taking energy pills with prozac.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    My psychiatrist specifically said that I would be fine, there wouldn't be any adverse drug interactions.
    Quote Originally Posted by AznExtasy View Post
    LMAO!!!!!!!!!!!!!!!!!!!!!!
    You can say that again.. not just on here but men in general. Guys are so damn lame, the only way they can halfway make up for it is by opening their wallets.

    Created by MyFitnessPal.com - Tools

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    Default Re: Antidepressants (ATTN: Mediocrity)

    If you look at the literature that came with the pristiq and read all the side effects there are tons of reactions and such that can happen for her to say that is unethical because she can't predict how things like diet pills with interact with an ssri hell alot of over the counter things can interact badly with them even vitamins and it says right on the bottle of energy and diet pills that it can cause serotonin syndrome if you take ssri's with them.I don't think that's what happened I think you just had a bad reaction to the pristiq. I've had worse from taking energy pills with antidepresants and benzos I almost had to be admited to the hospital as I thought I was having a nervous breakdown and it lasted 3 weeks, it was awful I thought I was going to die.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    I'm so sorry you went throught that. It does sound like a drug interaction.
    I accidentally took a 5-htp with my Lexapro once and had a similar reaction to what you explained.

    Also, I lost weight on Lexapro. I think if you normally overeat b/c of some underlying reason then take Lexapro there is a possibility you may stop resulting in weight loss. If you normally skip meals, etc. for some underlying reason and then get on it and get happy...you eat more resulting in a weight gain. I absolutely love love Lexpro , it has changed my life. I was not depressed, just had situational anxiety. I no longer have anxiety and everything is so clear now.

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    Default Re: Antidepressants (ATTN: Mediocrity)

    Have you been diagnosed with depression issues prior to this? Misdiagnosis could be at fault. Antidepressants + undiagnosed bipolar disorder could definitely send you out of your mind, and bipolar disorder could be behind the inability to sleep if you are in a manic, hypomanic, or mixed state.

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